NIR chemical imaging combines traditional NIR spectroscopy with microscopic and macroscopic imaging
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White Paper: Pharmaceutical tablets - to image or not to image?

What is NIR Chemical Imaging?

NIR Chemical Imaging is an exciting new analytical approach that enables the quantitative and spatial identification of species in a sample. This non-destructive technique combines traditional near infrared spectroscopy with microscopic and macroscopic imaging to produce an integrated near infrared system.

Why use NIR Chemical Imaging?

The functionality of many advanced materials (both man-made and natural) is based on the interaction and distribution of the sample components. Changes in the spatial localization of components may cause undesirable performance characteristics. Therefore the ability to chemically identify as well as locate these components is invaluable when it comes to sample understanding.

Benefits of NIR Chemical Imaging

Properties such as chemical domain characteristics, distribution of components, polymorph distribution and content, degree of hydration, location of contaminants or coating and layer thickness can all be determined. This knowledge can be used to help design and manufacture products with superior performance and also to reduce the issues associated with product scale-up. The ability to characterise both the spatial and chemical properties of a sample using this type of near infrared system can also be used for root cause analysis of manufacturing issues. Here a single rapid measurement enables the identification and spatial localization of sample components which can then be correlated with a sample performance metric, such as dissolution value.

The Technology of Near Infrared Systems

Based on infrared array detector technology, NIR Chemical Imaging systems bypass the time consuming data acquisition associated with mapping technologies. Spatial, chemical, structural and functional information can be derived from a single sample within a matter of minutes. Near infrared spectra are collected for each pixel on the array detector, creating a three dimensional cube consisting of both spatially resolved spectra and wavelength dependant images.

The SyNIRgi Near Infrared Chemical Imaging (NIR-CI) systems deliver this spatial and chemical information that, coupled with the ISys data analysis software, provides answers to the questions “What?”, “How much?”, and “Where?”. This complete integration of spatial and spectral information quite literally adds a new dimension to the data analysis: the ability to simultaneously examine the interdependency of the chemical and physical attributes of a sample or manufactured product. This new dimension forms the basis for unique information that cannot be obtained from other analytical methods.

The SyNIRgi NIR chemical imaging systems deliver spatial and chemical information

Contact us about the SyNIRgi Near Infrared System

 

I'm interested in Chemical Imaging:

 
NIR Chemical Imaging - Spectral Dimensions SyNIRgi
 
SyNIRgi NIR - Chemical Imaging
The SyNIRgi is available in two configurations, the standard version providing spectral coverage from 1200-2450 nm, and the SyNIRgi−S, a short wavelength version from 950 – 1720 nm. Designed with routine analytical measurements in mind, SyNIRgi increases productivity by adding significant capability for rapid acquisition of sample data. Typical applications range from pharmaceutical tablets and granules, to grains and seeds, to household and consumer products.
NIR Chemical Imaging - Spectral Dimensions SyNIRgi
 
NIR Chemical Imaging - ISys Software

ISys Chemical Imaging
ISys is the most powerful and comprehensive software package designed specifically for visualization and analysis of NIR Chemical Imaging data or chemical maps. It includes all the tools needed to intuitively understand your NIR Chemical Imaging data in spectral and spatial dimensions simultaneously.
NIR Chemical Imaging - ISys Software


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This product and/or its use may be covered by US patent numbers 6483112 and 6,690,464. Other patents pending.